Has a College Football game ever ended 69-45?
Exactly once. On November 24, 2023, Oklahoma beat TCU 69-45, and no College Football game before or since has ended that way. When it happened it was a scorigami, the first 69-45 in league history.
That makes 69-45 the 1820th most common final score out of 2,216 that have ever occurred in College Football. One point away, 70-45 has happened 1 times and 69-46 has happened never.