Has a College Football game ever ended 82-4?
Exactly once. On December 6, 1890, Cornell beat Fordham 82-4, and no College Football game before or since has ended that way. When it happened it was a scorigami, the first 82-4 in league history.
That makes 82-4 the 1819th most common final score out of 2,215 that have ever occurred in College Football. One point away, 83-4 has happened never and 82-5 has happened never.