Has a College Football game ever ended 9-1?
Exactly once. On October 15, 1881, Harvard beat Ottawa 9-1, and no College Football game before or since has ended that way. When it happened it was a scorigami, the first 9-1 in league history.
That makes 9-1 the 1820th most common final score out of 2,216 that have ever occurred in College Football. One point away, 10-1 has happened never and 9-2 has happened 14 times.