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Has an NFL game ever ended 22-21?

Yes. NFL has seen a final score of 22-21 23 times. It first happened on December 4, 1954, when Baltimore Colts beat Los Angeles Rams, and most recently on October 5, 2025, when Tennessee Titans beat Arizona Cardinals.

Where 22-21 sits among nearby NFL scores. Deeper blue means a score has happened more often; the outlined cell is the new one.

That makes 22-21 the 218th most common final score out of 1,090 that have ever occurred in NFL. One point away, 23-21 has happened 57 times and 22-22 has happened never.

Every 22-21 in NFL history

DateResultSeason
2025-10-05Tennessee Titans over Arizona Cardinals2025
2024-09-16Atlanta Falcons over Philadelphia Eagles2024
2020-10-22Philadelphia Eagles over New York Giants2020
2019-12-08New York Jets over Miami Dolphins2019
2018-01-06Tennessee Titans over Kansas City Chiefs2017Playoff
2016-12-24San Francisco 49ers over Los Angeles Rams2016
2014-10-26Detroit Lions over Atlanta Falcons2014
2013-12-08Green Bay Packers over Atlanta Falcons2013
2011-09-18Washington Redskins over Arizona Cardinals2011
2009-12-06Miami Dolphins over New England Patriots2009
2008-12-14San Diego Chargers over Kansas City Chiefs2008
1999-12-19New York Jets over Dallas Cowboys1999
1999-10-03Seattle Seahawks over Oakland Raiders1999
1997-12-14Seattle Seahawks over Oakland Raiders1997
1996-11-04Denver Broncos over Oakland Raiders1996
1995-01-08San Diego Chargers over Miami Dolphins1994Playoff
1994-11-20Seattle Seahawks over Tampa Bay Buccaneers1994
1994-11-06Miami Dolphins over Indianapolis Colts1994
1983-10-30Baltimore Colts over Philadelphia Eagles1983
1980-11-30San Diego Chargers over Philadelphia Eagles1980
1979-09-02Dallas Cowboys over St. Louis Cardinals1979
1961-12-10San Francisco 49ers over Green Bay Packers1961
1954-12-04Baltimore Colts over Los Angeles Rams1954

Open the NFL grid at 22-21