Has an NFL game ever ended 28-3?
Yes. NFL has seen a final score of 28-3 28 times. It first happened on November 8, 1936, when Detroit Lions beat Pittsburgh Pirates, and most recently on September 29, 2025, when Denver Broncos beat Cincinnati Bengals.
That makes 28-3 the 186th most common final score out of 1,090 that have ever occurred in NFL. One point away, 29-3 has happened 7 times and 28-4 has happened never.