Has an NFL game ever ended 29-21?
It has. 29-21 has been a NFL final 20 times in 18,234 games. The first was New Orleans Saints beat Green Bay Packers on November 28, 1971; the latest was Washington Commanders beat New York Giants on December 14, 2025.
That makes 29-21 the 256th most common final score out of 1,095 that have ever occurred in NFL. One point away, 30-21 has happened 31 times and 29-22 has happened 8 times.