Has an NFL game ever ended 38-0?
Yes. NFL has seen a final score of 38-0 23 times. It first happened on October 24, 1920, when Buffalo All-Americans beat Toledo Maroons, and most recently on January 5, 2025, when Denver Broncos beat Kansas City Chiefs.
That makes 38-0 the 218th most common final score out of 1,090 that have ever occurred in NFL. One point away, 39-0 has happened 5 times and 38-1 has happened never.