Has an NFL game ever ended 41-22?
Yes. NFL has seen a final score of 41-22 4 times. It first happened on October 11, 1987, when Dallas Cowboys beat Philadelphia Eagles, and most recently on November 16, 2025, when San Francisco 49ers beat Arizona Cardinals.
That makes 41-22 the 563rd most common final score out of 1,090 that have ever occurred in NFL. One point away, 42-22 has happened 1 times and 41-23 has happened 7 times. At one point the score disappeared for 26 years, between 1995 and 2021.
Every 41-22 in NFL history
| Date | Result | Season | |
|---|---|---|---|
| 2025-11-16 | San Francisco 49ers over Arizona Cardinals | 2025 | |
| 2021-12-05 | Los Angeles Chargers over Cincinnati Bengals | 2021 | |
| 1995-12-24 | Miami Dolphins over St. Louis Rams | 1995 | |
| 1987-10-11 | Dallas Cowboys over Philadelphia Eagles | 1987 |