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Has an NFL game ever ended 45-17?

Yes. NFL has seen a final score of 45-17 26 times. It first happened on November 10, 1946, when New York Giants beat Philadelphia Eagles, and most recently on December 7, 2025, when Los Angeles Rams beat Arizona Cardinals.

Where 45-17 sits among nearby NFL scores. Deeper blue means a score has happened more often; the outlined cell is the new one.

That makes 45-17 the 197th most common final score out of 1,095 that have ever occurred in NFL. One point away, 46-17 has happened never and 45-18 has happened never.

Every 45-17 in NFL history

DateResultSeason
2025-12-07Los Angeles Rams over Arizona Cardinals2025
2021-11-14Buffalo Bills over New York Jets2021
2021-10-10Tampa Bay Buccaneers over Miami Dolphins2021
2015-11-22Tampa Bay Buccaneers over Philadelphia Eagles2015
2013-09-22Seattle Seahawks over Jacksonville Jaguars2013
2012-01-01New Orleans Saints over Carolina Panthers2011
2010-12-26Green Bay Packers over New York Giants2010
2005-11-20Kansas City Chiefs over Houston Texans2005
2004-12-19Kansas City Chiefs over Denver Broncos2004
2004-11-29Green Bay Packers over St. Louis Rams2004
2003-12-14Kansas City Chiefs over Detroit Lions2003
2003-10-19New Orleans Saints over Atlanta Falcons2003
2002-01-20St. Louis Rams over Green Bay Packers2001Playoff
2000-12-03San Francisco 49ers over San Diego Chargers2000
1997-11-23Green Bay Packers over Dallas Cowboys1997
1993-09-27Pittsburgh Steelers over Atlanta Falcons1993
1984-11-11Green Bay Packers over Minnesota Vikings1984
1972-10-29Oakland Raiders over Los Angeles Rams1972
1971-12-12San Diego Chargers over Denver Broncos1971
1969-12-07Atlanta Falcons over New Orleans Saints1969
1968-12-15Houston Oilers over Boston Patriots1968
1968-11-03St. Louis Cardinals over Philadelphia Eagles1968
1964-12-13Baltimore Colts over Washington Redskins1964
1961-09-16Boston Patriots over Denver Broncos1961
1957-10-13Baltimore Colts over Green Bay Packers1957
1946-11-10New York Giants over Philadelphia Eagles1946

Open the NFL grid at 45-17