Has an International Rugby game ever ended 60-21?
Exactly once. On March 20, 1999, Wales beat Italy 60-21, and no International Rugby game before or since has ended that way. When it happened it was a scorigami, the first 60-21 in league history.
That makes 60-21 the 510th most common final score out of 844 that have ever occurred in International Rugby. One point away, 61-21 has happened 1 times and 60-22 has happened never.