Has an AFL game ever ended 110-51?
Exactly once. On May 4, 1946, Richmond beat St Kilda 110-51, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 110-51 in league history.
That makes 110-51 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 111-51 has happened 1 times and 110-52 has happened 1 times.