Has an AFL game ever ended 110-52?
Exactly once. On May 7, 1955, Richmond beat Sydney 110-52, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 110-52 in league history.
That makes 110-52 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 111-52 has happened 4 times and 110-53 has happened 1 times.