Has an AFL game ever ended 110-53?
Exactly once. On June 9, 1996, Hawthorn beat Fremantle 110-53, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 110-53 in league history.
That makes 110-53 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 111-53 has happened 1 times and 110-54 has happened 5 times.