Has an AFL game ever ended 125-43?
Exactly once. On August 23, 1930, Geelong beat Hawthorn 125-43, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 125-43 in league history.
That makes 125-43 the 3884th most common final score out of 6,649 that have ever occurred in AFL. One point away, 126-43 has happened 3 times and 125-44 has happened never.