Has an AFL game ever ended 125-46?
Exactly once. On July 28, 1990, Essendon beat Richmond 125-46, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 125-46 in league history.
That makes 125-46 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 126-46 has happened 2 times and 125-47 has happened never.