Has an AFL game ever ended 157-44?
Exactly once. On August 11, 2013, Fremantle beat GWS 157-44, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 157-44 in league history.
That makes 157-44 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 158-44 has happened never and 157-45 has happened never.