Has an AFL game ever ended 157-52?
Exactly once. On July 15, 1944, Melbourne beat Hawthorn 157-52, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 157-52 in league history.
That makes 157-52 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 158-52 has happened never and 157-53 has happened never.