Has an AFL game ever ended 163-38?
Exactly once. On August 19, 1911, Essendon beat St Kilda 163-38, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 163-38 in league history.
That makes 163-38 the 3883rd most common final score out of 6,649 that have ever occurred in AFL. One point away, 164-38 has happened never and 163-39 has happened never.