Has an AFL game ever ended 163-42?
Exactly once. On August 25, 2013, Richmond beat GWS 163-42, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 163-42 in league history.
That makes 163-42 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 164-42 has happened never and 163-43 has happened never.