Has an AFL game ever ended 50-19?
Exactly once. On August 22, 2020, Fremantle beat Sydney 50-19, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 50-19 in league history.
That makes 50-19 the 3884th most common final score out of 6,649 that have ever occurred in AFL. One point away, 51-19 has happened 1 times and 50-20 has happened 1 times.