Has an AFL game ever ended 53-28?
Exactly once. On June 22, 1907, Geelong beat Essendon 53-28, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 53-28 in league history.
That makes 53-28 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 54-28 has happened never and 53-29 has happened 2 times.