Has an MLB game ever ended 16-12?
It has. 16-12 has been a MLB final 28 times in 235,971 games. The first was Philadelphia Athletics beat Allegheny Club (none) on July 31, 1883; the latest was Kansas City Royals beat New York Mets on July 7, 2026.
That makes 16-12 the 159th most common final score out of 330 that have ever occurred in MLB. One point away, 17-12 has happened 9 times and 16-13 has happened 19 times. At one point the score disappeared for 26 years, between 1980 and 2006.