Has an NCAA Men's Basketball game ever ended 121-54?

Exactly once. On November 15, 2008, Lipscomb Bisons beat Oakland City Mighty Oaks 121-54, and no NCAA Men's Basketball game before or since has ended that way. When it happened it was a scorigami, the first 121-54 in league history.

Where 121-54 sits among nearby NCAA Men's Basketball scores. Deeper blue means a score has happened more often; the outlined cell is the new one.

That makes 121-54 the 3013th most common final score out of 3,845 that have ever occurred in NCAA Men's Basketball. One point away, 122-54 has happened 1 times and 121-55 has happened 1 times.

Every 121-54 in NCAA Men's Basketball history

Date	Result	Season
2008-11-15	Lipscomb Bisons over Oakland City Mighty Oaks	2009

Open the NCAA Men's Basketball grid at 121-54