Has an NFL game ever ended 16-3?
It has. 16-3 has been a NFL final 29 times in 18,234 games. The first was Chicago Cardinals beat Green Bay Packers on October 15, 1922; the latest was New England Patriots beat Los Angeles Chargers on January 11, 2026.
That makes 16-3 the 184th most common final score out of 1,095 that have ever occurred in NFL. One point away, 17-3 has happened 65 times and 16-4 has happened never. At one point the score disappeared for 46 years, between 1922 and 1968.