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Has an NFL game ever ended 43-21?

It has. 43-21 has been a NFL final 3 times in 18,234 games. The first was St. Louis Cardinals beat Los Angeles Rams on September 23, 1960; the latest was Buffalo Bills beat Washington Football Team on September 26, 2021.

Where 43-21 sits among nearby NFL scores. Deeper blue means a score has happened more often; the outlined cell is the new one.

That makes 43-21 the 632nd most common final score out of 1,095 that have ever occurred in NFL. One point away, 44-21 has happened 9 times and 43-22 has happened 1 times. At one point the score disappeared for 54 years, between 1960 and 2014.

Every 43-21 in NFL history

DateResultSeason
2021-09-26Buffalo Bills over Washington Football Team2021
2014-11-02New England Patriots over Denver Broncos2014
1960-09-23St. Louis Cardinals over Los Angeles Rams1960

Open the NFL grid at 43-21