Has an NFL game ever ended 45-22?
Exactly once. On October 25, 1979, Oakland Raiders beat San Diego Chargers 45-22, and no NFL game before or since has ended that way. When it happened it was a scorigami, the first 45-22 in league history.
That makes 45-22 the 838th most common final score out of 1,090 that have ever occurred in NFL. One point away, 46-22 has happened never and 45-23 has happened 1 times.
Every 45-22 in NFL history
| Date | Result | Season | |
|---|---|---|---|
| 1979-10-25 | Oakland Raiders over San Diego Chargers | 1979 |